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WP1 – Project management
WP2 – Randomisation
WP3 – Extrapolation
WP4 – Adaptive design
WP5 – Optimal design
WP6 – Pharmacogenetics
WP7 – Simulation
WP 8 – Genetic factors
WP 9 – Decision analysis
WP10 – Biomarker
WP11 – Dissemination
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Uniklinik Aachen
RWTH Aachen
Ruhr-Universität Bochum
MUW – Statistics
MUW – Paediatrics
INSERM
CRP Santé
Uppsala Universitet
Politechnika Wrocławska
CHALMERS University
Universiteit Hasselt
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WP no.
Work package title
1
Project Management and Coordination
2
Assessment of randomisation procedures and randomisation based tests in small population groups
3
Extrapolating dose-response information to small population groups
4
Adaptive design studies in small population groups
5
Optimal design in mixed models to analyse studies in small population groups
6
Design of pharmacogenetic small population group trials including cross-over trials, n-of-1 trials and enrichment trials
7
Simulation of clinical trials in small population groups
8
Genetic factors influencing the response to the therapy in small population group trials
9
Decision analysis in small population groups
10
Biomarker surrogate endpoints in small population groups
11
Dissemination
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