{"id":1600,"date":"2016-07-26T10:18:04","date_gmt":"2016-07-26T09:18:04","guid":{"rendered":"http:\/\/www.ideal.rwth-aachen.de\/?p=1600"},"modified":"2016-07-26T10:18:04","modified_gmt":"2016-07-26T09:18:04","slug":"ralf-dieter-hilgers-publishes-paper-on-new-developments-for-small-population-group-trials","status":"publish","type":"post","link":"https:\/\/www.ideal.rwth-aachen.de\/?p=1600","title":{"rendered":"Ralf-Dieter Hilgers publishes paper on new developments for small population group trials"},"content":{"rendered":"<p>With his colleagues Kit Roes and Nigel Stellard, Prof. Ralf-Dieter Hilgers published a precedent-setting paper on methodology for small population group trials. The paper \u201cDirections for new developments on statistical design and analysis of small population group trials\u201d addresses the challenges presented by the EMA\/CHMP guideline and discusses recent developments in extrapolation. It was issued in the Orphanet Journal of Rare Diseases, and can be accessed <a href=\"http:\/\/ojrd.biomedcentral.com\/articles\/10.1186\/s13023-016-0464-5\">here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>With his colleagues Kit Roes and Nigel Stellard, Prof. Ralf-Dieter Hilgers published a precedent-setting paper on methodology for small population group trials. The paper \u201cDirections for new developments on statistical design and analysis of small population group trials\u201d addresses the challenges presented by the EMA\/CHMP guideline and discusses recent developments in extrapolation. It was issued [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-1600","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/posts\/1600","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1600"}],"version-history":[{"count":1,"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/posts\/1600\/revisions"}],"predecessor-version":[{"id":1602,"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/posts\/1600\/revisions\/1602"}],"wp:attachment":[{"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1600"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1600"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1600"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}