{"id":410,"date":"2013-09-06T12:16:53","date_gmt":"2013-09-06T10:16:53","guid":{"rendered":"http:\/\/www.ideal.rwth-aachen.de\/?page_id=410"},"modified":"2013-11-20T15:48:34","modified_gmt":"2013-11-20T13:48:34","slug":"uppsala-universitet","status":"publish","type":"page","link":"https:\/\/www.ideal.rwth-aachen.de\/?page_id=410","title":{"rendered":"Uppsala Universitet"},"content":{"rendered":"<\/div><\/div><\/div><!-- close content main div --><\/div><\/div><div id='av_section_1' class='avia-section main_color avia-section-default avia-no-shadow avia-bg-style-scroll   container_wrap fullsize' style = 'background-image: '  ><div class='container' ><div class='template-page content  av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-410'><div class='entry-content-wrapper clearfix'>\n<div class=\"flex_column av_one_fourth  flex_column_div first  \" ><div class='avia-image-container avia_animated_image avia_animate_when_almost_visible left-to-right av-styling-    avia-align-left '  itemprop=\"ImageObject\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\"  ><div class='avia-image-container-inner'><div class='avia-image-overlay-wrap'><a href='http:\/\/www.uu.se' class='avia_image'  ><img class='avia_image ' src='http:\/\/www.ideal.rwth-aachen.de\/wp-content\/uploads\/2013\/08\/uulogo_grey.png' alt='' title=''  itemprop=\"thumbnailUrl\"  \/><\/a><\/div><\/div><\/div><\/div><div class=\"flex_column av_three_fourth  flex_column_div   \" ><p><div style='padding-bottom:10px; ' class='av-special-heading av-special-heading-h3    '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >UPPSALA UNIVERSITET<\/h3><div class='special-heading-border'><div class='special-heading-inner-border' ><\/div><\/div><\/div><br \/>\n<div style='padding-bottom:10px; ' class='av-special-heading av-special-heading-h3  blockquote modern-quote  '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Department of Pharmaceutical Biosciences<\/h3><div class='special-heading-border'><div class='special-heading-inner-border' ><\/div><\/div><\/div><br \/>\n\t<div  class='av_promobox  avia-button-yes '>\t\t<div class='avia-promocontent'><\/p>\n<address>Department of Pharmaceutical Biosciences<br \/>\nPO Box 591<br \/>\n751 24 Uppsala<br \/>\nSweden<\/address>\n<p>\n<\/div><div class='avia-button-wrap avia-button-right '><a href='https:\/\/maps.google.de\/maps?q=59.842055,17.632615&amp;num=1&amp;t=h&amp;z=17'  class='avia-button   avia-icon_select-yes-left-icon avia-color-orange avia-size-small avia-position-right '  target=\"_blank\"   ><span class='avia_button_icon avia_button_icon_left ' aria-hidden='true' data-av_icon='\ue842' data-av_iconfont='entypo-fontello'><\/span><span class='avia_iconbox_title' >Google Maps<\/span><\/a><\/div>\t<\/div><\/p><\/div><\/div><\/div><\/div><!-- close content main div --><\/div><\/div><div id='av_section_2' class='avia-section alternate_color avia-section-small avia-shadow avia-bg-style-scroll   container_wrap fullsize' style = 'background-image: '  ><div class='container' ><div class='template-page content  av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-410'><div class='entry-content-wrapper clearfix'>\n<div style='padding-bottom:7px; ' class='av-special-heading av-special-heading-h3  blockquote modern-quote  '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Our Staff<\/h3><div class='special-heading-border'><div class='special-heading-inner-border' ><\/div><\/div><\/div>\n<div class=\"flex_column av_one_third  flex_column_div first  \" ><section class='avia-team-member  '  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Person\" ><div class='team-img-container'><img class='avia_image avia_image_team' src='http:\/\/www.ideal.rwth-aachen.de\/wp-content\/uploads\/2013\/09\/Mats_1-495x400.jpg' alt='Prof. Mats O. Karlsson'  itemprop=\"image\"  \/><div class='team-social'><div class='team-social-inner'><span class='hidden av_member_url_markup '  itemprop=\"email\" >mailto:mats.karlsson@farmbio.uu.se<\/span><a rel='v:url' data-avia-tooltip=\"E-mail\" target='_blank' class=' avia-team-icon ' href='mailto:mats.karlsson@farmbio.uu.se' aria-hidden='true' data-av_icon='\ue805' data-av_iconfont='entypo-fontello'><\/a><span class='hidden av_member_url_markup '  itemprop=\"url\" >http:\/\/www.farmbio.uu.se\/research\/researchgroups\/pharmacometrics\/<\/span><a rel='v:url' data-avia-tooltip=\"Website\" target='_blank' class=' avia-team-icon ' href='http:\/\/www.farmbio.uu.se\/research\/researchgroups\/pharmacometrics\/' aria-hidden='true' data-av_icon='\ue8b1' data-av_iconfont='entypo-fontello'><\/a><\/div><\/div><\/div><h3 class='team-member-name'   itemprop=\"name\" >Prof. Mats O. Karlsson<\/h3><div class='team-member-job-title '   itemprop=\"jobTitle\" >WP7 \u2013 lead<\/div><div class='team-member-description '  itemprop=\"description\"  ><p>E-mail: <a href=\"mailto:mats.karlsson@farmbio.uu.se\">mats.karlsson@farmbio.uu.se<\/a><\/p>\n<\/div><span class='hidden team-member-affiliation'  itemprop=\"affiliation\" >IDEAL<\/span><\/section><\/div><div class=\"flex_column av_one_third  flex_column_div   \" ><section class='avia-team-member  '  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Person\" ><div class='team-img-container'><img class='avia_image avia_image_team' src='http:\/\/www.ideal.rwth-aachen.de\/wp-content\/uploads\/2013\/09\/Kristin_2-495x400.jpg' alt='Dr. Kristin Karlsson'  itemprop=\"image\"  \/><div class='team-social'><div class='team-social-inner'><span class='hidden av_member_url_markup '  itemprop=\"email\" >mailto:kristin.karlsson@farmbio.uu.se<\/span><a rel='v:url' data-avia-tooltip=\"E-mail\" target='_blank' class=' avia-team-icon ' href='mailto:kristin.karlsson@farmbio.uu.se' aria-hidden='true' data-av_icon='\ue805' data-av_iconfont='entypo-fontello'><\/a><span class='hidden av_member_url_markup '  itemprop=\"url\" >http:\/\/www.farmbio.uu.se\/research\/researchgroups\/pharmacometrics\/<\/span><a rel='v:url' data-avia-tooltip=\"Website\" target='_blank' class=' avia-team-icon ' href='http:\/\/www.farmbio.uu.se\/research\/researchgroups\/pharmacometrics\/' aria-hidden='true' data-av_icon='\ue8b1' data-av_iconfont='entypo-fontello'><\/a><\/div><\/div><\/div><h3 class='team-member-name'   itemprop=\"name\" >Dr. Kristin Karlsson<\/h3><div class='team-member-job-title '   itemprop=\"jobTitle\" >WP7 \u2013 Postdoc<\/div><div class='team-member-description '  itemprop=\"description\"  ><p>E-mail: <a href=\"mailto:kristin.karlsson@farmbio.uu.se\">kristin.karlsson@farmbio.uu.se<\/a><\/p>\n<\/div><span class='hidden team-member-affiliation'  itemprop=\"affiliation\" >IDEAL<\/span><\/section><\/div><div class=\"flex_column av_one_third  flex_column_div   \" ><section class='avia-team-member  '  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/Person\" ><div class='team-img-container'><img class='avia_image avia_image_team' src='http:\/\/www.ideal.rwth-aachen.de\/wp-content\/uploads\/2013\/09\/AG_2-495x400.jpg' alt='M.Sc. Anne-Ga\u00eblle Dosne'  itemprop=\"image\"  \/><div class='team-social'><div class='team-social-inner'><span class='hidden av_member_url_markup '  itemprop=\"email\" >mailto:annegaelle.dosne@farmbio.uu.se<\/span><a rel='v:url' data-avia-tooltip=\"E-mail\" target='_blank' class=' avia-team-icon ' href='mailto:annegaelle.dosne@farmbio.uu.se' aria-hidden='true' data-av_icon='\ue805' data-av_iconfont='entypo-fontello'><\/a><span class='hidden av_member_url_markup '  itemprop=\"url\" >http:\/\/www.farmbio.uu.se\/research\/researchgroups\/pharmacometrics\/<\/span><a rel='v:url' data-avia-tooltip=\"Website\" target='_blank' class=' avia-team-icon ' href='http:\/\/www.farmbio.uu.se\/research\/researchgroups\/pharmacometrics\/' aria-hidden='true' data-av_icon='\ue8b1' data-av_iconfont='entypo-fontello'><\/a><\/div><\/div><\/div><h3 class='team-member-name'   itemprop=\"name\" >M.Sc. Anne-Ga\u00eblle Dosne<\/h3><div class='team-member-job-title '   itemprop=\"jobTitle\" >WP7 \u2013 PhD student<\/div><div class='team-member-description '  itemprop=\"description\"  ><p>E-mail: <a href=\"mailto:annegaelle.dosne@farmbio.uu.se\">annegaelle.dosne@farmbio.uu.se<\/a><\/p>\n<\/div><span class='hidden team-member-affiliation'  itemprop=\"affiliation\" >IDEAL<\/span><\/section><\/div>\n<\/p>\n<\/div><\/div><\/div><!-- close content main div --><\/div><\/div><div id='uu' class='avia-section main_color avia-section-default avia-shadow avia-bg-style-scroll   container_wrap fullsize' style = 'background-image: '  ><div class='container' ><div class='template-page content  av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-410'><div class='entry-content-wrapper clearfix'>\n<div style='padding-bottom:10px; ' class='av-special-heading av-special-heading-h3    '><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >About<\/h3><div class='special-heading-border'><div class='special-heading-inner-border' ><\/div><\/div><\/div>\n<p><section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock  '   itemprop=\"text\" ><p><b>Uppsala University<\/b> is the oldest university in the Nordic countries, established already in 1477. The university is consistently ranked among the top 100 universities in the world. Education and research are divided into nine faculties: theology, law, arts, languages, social sciences, educational sciences, medicine, pharmacy, science and technology. The faculty of pharmacy is divided into three departments that in their turn are divided into several research groups. Prof. Mats O. Karlsson is deputy head of the Department of Pharmaceutical Biosciences and the leader for the Pharmacometric research group. The Pharmacometric research group, consist of 40 + researchers (senior researchers, post-doctoral fellows and PhD students).<\/p>\n<p>Research at the <b>Pharmacometrics Group<\/b> can be divided into four main areas. First, development and evaluation of methods for efficient and robust model building. This involves development of estimation algorithms, methods for model diagnosis and sequential procedures for model building. The result of the research, when applicable, is made available as free software. Second, so-called platform models are being developed for the use in specific therapeutic areas or for particular therapeutic\/pharmacological principles. Such a model may involve the time-course of a biomarker or a system of biomarkers during normal, diseased and\/or provoked situations. The third research area concerns utilisation of the developed models for the purpose of designing studies, deciding upon dosing strategies and other decisions. Fourth, we also do analyses of dose-concentration-response data from trials to understand therapies with existing drugs with the aim of allowing improved therapy.<\/p>\n<p><b>Main Project Tasks and Experiences related to the project: <\/b>Main methodological research areas of the Department of Pharamceutical Biosciences are biochemical pharmacology, drug safety and toxicology, translational PKPD and pharmacometics. The Department of Pharamceutical Biosciences is fully responsible for the work package \u201cClinical trial simulations and non-linear mixed effects modelling in small population groups\u201d.<\/p>\n<p><b>Key Personnel: <\/b><\/p>\n<p style=\"padding-left: 30px;\"><b><i>Prof. Mats O. Karlsson<\/i><\/b> is professor of pharmacometrics at Uppsala University, Sweden where he leads a group of more than 40 researchers. He received his PhD in pharmacokinetics in 1989 and has been a research fellow at University of Glasgow and University of California, San Francisco and a visiting professor at Georgetown University, Washington DC. He has received the Uppsala University Oscar Prize, the Giorgio Segr\u00e9 Prize from EUFEPS and an Honorary Fellowship Award from American Collage of Clinical Pharmacology. His research interests focus on methodological aspects of non-linear mixed effects model building (\u201cpopulation modeling\u201d) and applications of PKPD modeling to problems in drug development and drug usage. He has published over 200 original research articles in this area. Mats is the academic leader of the IMI Consortium DDMoRe (Drug Disease Model Resources) and is active as an investigator also in the IMI Consortiums PreDiCT-TB and OrBiTo (Oral biopharmaceutics tools).<\/p>\n<p style=\"padding-left: 30px;\"><b>Dr. Kristin E. Karlsson<\/b> received her PhD in pharmacokinetics and drug therapy in December 2010 at Uppsala University, with the thesis \u201cBenefits of Pharmacometric Model-Based Design and Analysis of Clinical Trials\u201d. Since then she has held a position as post doc at Uppsala University. Prior to her thesis studied Kristin earned a Master of Science degree in Chemical engineering, with an emphasis on drug development. Between September 2007 and April 2009, Kristin worked as a pharmacometrician at AstraZeneca R&amp;D in S\u00f6dert\u00e4lje, Sweden. Her current research focuses on the application of pharmacometric models in analysis and design on clinical trials, foremost in terms of development of new methodology but also in actual exposure-response analyses.<\/p>\n<\/div><\/section>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":60,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-410","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/410","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=410"}],"version-history":[{"count":10,"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/410\/revisions"}],"predecessor-version":[{"id":764,"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/410\/revisions\/764"}],"up":[{"embeddable":true,"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=\/wp\/v2\/pages\/60"}],"wp:attachment":[{"href":"https:\/\/www.ideal.rwth-aachen.de\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=410"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}